Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog

Oke, M. et al. (2008) Unusual chromophore and cross-links in ranasmurfin: a blue protein from the foam nests of a tropical frog. Angewandte Chemie (International Edition), 47(41), 7853 -7856. (doi:10.1002/anie.200802901)

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Abstract

A smurfin' good structure: The 1.16 Å resolution crystal structure of ranasmurfin, a blue protein extracted from the foam nests of the Malaysian tree frog Polypedates leucomystax, reveals unusual posttranslational chemical modifications. The chromophore involves an extended Zn-coordinated four-residue (Lys-Tyr-Tyr-Lys) inter-subunit cross-link of a kind not previously reported.

Item Type:Articles
Keywords:chromophores, cofactors, foam, protein modifications, protein structures
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Kennedy, Professor Malcolm and Cooper, Professor Alan
Authors: Oke, M., Ching, R.T.Y., Carter, L.G., Johnson, K.A., Liu, H., McMahon, S.A., White, M.F., Bloch, C., Botting, C.H., Walsh, M.A., Latiff, A.A., Kennedy, M.W., Cooper, A., and Naismith, J.H.
Subjects:Q Science > QD Chemistry
College/School:College of Science and Engineering > School of Chemistry
College of Medical Veterinary and Life Sciences > School of Life Sciences
Journal Name:Angewandte Chemie (International Edition)
Journal Abbr.:Angew Chem Int Ed Engl
Publisher:Wiley - V C H Verlag GmbH & Co. KGaA
ISSN:1433-7851
ISSN (Online):1521-3773
Published Online:09 September 2008

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