Reprinted Article “The Fate of the Claudicant—A Prospective Study of 1969 Claudicants"

Dormandy, J.A. and Murray, G.D. (2011) Reprinted Article “The Fate of the Claudicant—A Prospective Study of 1969 Claudicants". European Journal of Vascular and Endovascular Surgery, 42(Supp 1), S4-S6. (doi: 10.1016/j.ejvs.2011.06.014)

Abstract

A prospective study of 1969 patients with intermittent claudication receiving placebo medication for a minimum of 1 year is reported. Patients were carefully monitored and only four patients were lost to follow-up. Annual mortality was 4.3%. Thirty-six patients developed a definite myocardial infarction, 27 a major stroke, 32 required a major amputation and 111 required surgical or radiological intervention for deteriorating ischaemia of the leg. The entry characteristics of the patients were analysed as a predictor of serious cardiovascular events. The most sensitive predictors of total mortality were age, history of coronary heart disease and an ankle/arm pressure ratio below 0.5. Of the laboratory measurements performed only the initial white cell count was a significant predictor of myocardial infarction, stroke and vascular deaths. (C) 2011 Published by Elsevier Ltd on behalf of European Society for Vascular Surgery

• Item Type: Articles
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Murray, Ms Gillian
• Authors: Dormandy, J.A., and Murray, G.D.
• Subjects: R Medicine > RC Internal medicine; R Medicine > RD Surgery
• College/School: College of Medical Veterinary and Life Sciences > School of Infection & Immunity
• Journal Name: European Journal of Vascular and Endovascular Surgery
• Publisher: Elsevier
• ISSN: 1078-5884