Effect of nesiritide in patients with acute decompensated heart failure

O'Connor, C.M. et al. (2011) Effect of nesiritide in patients with acute decompensated heart failure. New England Journal of Medicine, 365(1), pp. 32-43. (doi:10.1056/NEJMoa1100171)

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Abstract

Nesiritide was not associated with an increase or a decrease in the rate of death and rehospitalization and had a small, nonsignificant effect on dyspnea when used in combination with other therapies. It was not associated with a worsening of renal function, but it was associated with an increase in rates of hypotension. On the basis of these results, nesiritide cannot be recommended for routine use in the broad population of patients with acute heart failure.

Item Type:Articles
Additional Information:Correction: Effect of Nesiritide in Patients with Acute Decompensated Heart Failure (Original Article, N Engl J Med 2011 ; 365 : 32 - 43) . The author listed as “W.H. Wilson” (page 32), should have been listed as “W.H.W. Tang.” The article is correct at NEJM.org.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McMurray, Professor John
Authors: O'Connor, C.M., Starling, R.C., Hernandez, A.F., Armstrong, P.W., Dickstein, K., Hasselblad, V., Heizer, G.M., Komajda, M., Massie, B.M., McMurray, J.J.V., Nieminen, M.S., Reist, C.J., Rouleau, J.L., Swedberg, K., Adams, K.F., Anker, S.D., Atar, D., Battler, A., Botero, R., Bohidar, N.R., Butler, J., Clausell, N., Corbalán, R., Costanzo, M.R., Dahlstrom, U., Deckelbaum, L.I., Diaz, R., Dunlap, M.E., Ezekowitz, J.A., Feldman, D., Felker, G.M., Fonarow, G.C., Gennevois, D., Gottlieb, S.S., Hill, J.A., Hollander, J.E., Howlett, J.G., Hudson, M.P., Kociol, R.D., Krum, H., Laucevicius, A., Levy, W.C., Méndez, G.F., Metra, M., Mittal, S., Oh, B.-H., Pereira, N.L., Ponikowski, P., Tang, W.H.W., Wilson, W.H., Tanomsup, S., Teerlink, J.R., Triposkiadis, F., Troughton, R.W., Voors, A.A., Whellan, D.J., Zannad, F., and Califf, R.M.
Subjects:R Medicine > RC Internal medicine
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:New England Journal of Medicine
Journal Abbr.:NEJM
Publisher:Massachusetts Medical Society
ISSN:0028-4793
ISSN (Online):1533-4406

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