Antimicrobial effectiveness of furazolidone against metronidazole-resistant strains of Helicobacter pylori

Safaralizadeh, R., Siavoshi, F., Malekzadeh, R., Akbari, M.R., Derakhshan, M.H., Sohrabi, M.R. and Massarrat, S. (2006) Antimicrobial effectiveness of furazolidone against metronidazole-resistant strains of Helicobacter pylori. Eastern Mediterranean Health Journal, 12(3-4), pp. 286-293.

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Abstract

The occurrence of strains resistant to metronidazole is causing failure of the 4-drug regimen for eradication of Helicobacter pylori in the Islamic Republic of Iran. This study compared the in vitro efficacy of furazolidone with metronidazole, clarithromycin, amoxicillin and tetracycline in 70 H. pylori isolates from dyspeptic patients. Of the isolates, 33% were resistant to metronidazole but all were susceptible to furazolidone. Furazolidone could be considered as an appropriate substitute for metronidazole for H. pylori infections.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Derakhshan, Dr Mohammad
Authors: Safaralizadeh, R., Siavoshi, F., Malekzadeh, R., Akbari, M.R., Derakhshan, M.H., Sohrabi, M.R., and Massarrat, S.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Eastern Mediterranean Health Journal
ISSN:1020-3397
ISSN (Online):1687-1634

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