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Functional gene testing of the Glu298Asp polymorphism of the endothelial NO synthase

Schneider, M.P., Erdmann, J., Delles, C., Fleck, E., Regitz-Zagrosek, V., and Schmieder, R.E. (2000) Functional gene testing of the Glu298Asp polymorphism of the endothelial NO synthase. Journal of Hypertension, 18 (12). pp. 1767-73. ISSN 0263-6352

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Abstract

At a power of 80%, we can exclude a relevant effect on endothelium-dependent vasodilation due to the eNOS Glu298Asp polymorphism. Thus, our functional genetic study does not suggest any biological effect of the eNOS Glu298Asp genotype on the cardiovascular system via an influence on endothelium-dependent vasodilation.

Item Type:Article
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Schneider, Dr Markus
Authors: Schneider, M.P., Erdmann, J., Delles, C., Fleck, E., Regitz-Zagrosek, V., and Schmieder, R.E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences > Cardiovascular Science
Journal Name:Journal of Hypertension
ISSN:0263-6352

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