Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension

Schlaich, M.P., Klingbeil, A.U., Jacobi, J., Delles, C. , Schneider, M.P., Schmidt, B.M. and Schmieder, R.E. (2002) Altered aldosterone response to salt intake and angiotensin II infusion in young normotensive men with parental history of arterial hypertension. Journal of Hypertension, 20(1), pp. 117-24.

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Abstract

Our findings suggest that young normotensive subjects with parental history of arterial hypertension are characterized by an inadequate suppression of aldosterone production in response to salt loading and an exaggerated and prolonged hyper-responsiveness of aldosterone secretion in response to Ang II. This might contribute to the increased risk for the development of essential hypertension in subjects with positive family history of arterial hypertension.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Schneider, Dr Markus and Delles, Professor Christian
Authors: Schlaich, M.P., Klingbeil, A.U., Jacobi, J., Delles, C., Schneider, M.P., Schmidt, B.M., and Schmieder, R.E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Journal of Hypertension
ISSN:0263-6352

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