MacKenzie, S. M. , Connell, J. M.C. and Davies, E. (2012) Non-adrenal synthesis of aldosterone: A reality check. Molecular and Cellular Endocrinology, 350(2), pp. 163-167. (doi: 10.1016/j.mce.2011.06.026)
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Publisher's URL: http://dx.doi.org/10.1016/j.mce.2011.06.026
Abstract
Advances in the sensitivity of molecular techniques during the 1990s led to a flurry of studies that supported the existence of extra-adrenal sites of aldosterone production in various tissues including the brain and the heart. Subsequent work was often conflicting or ambiguous, leading many to question whether extra-adrenal aldosterone was of any physiological importance, or whether it even existed. In this article, we review these studies and, in light of this evidence, discuss whether the current lack of interest in extra-adrenal aldosterone biosynthesis is justified
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Davies, Professor Eleanor and Connell, Professor John and MacKenzie, Dr Scott |
Authors: | MacKenzie, S. M., Connell, J. M.C., and Davies, E. |
College/School: | College of Medical Veterinary and Life Sciences > School of Cardiovascular & Metabolic Health College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing |
Journal Name: | Molecular and Cellular Endocrinology |
Publisher: | Elsevier Ireland Ltd |
ISSN: | 0303-7207 |
ISSN (Online): | 1872-8057 |
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