Evaluation of the Cozart® RapiScan drug test system for opiates and cocaine in oral fluid

Cooper, G., Wilson, L., Reid, C., Main, L. and Hand, C. (2005) Evaluation of the Cozart® RapiScan drug test system for opiates and cocaine in oral fluid. Forensic Science International, 150(2-3), pp. 239-243. (doi:10.1016/j.forsciint.2004.12.042)

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Abstract

The purpose of this study was to evaluate the efficiency of the Cozart<sup>®</sup> RapiScan (CRS) drug test system for detecting opiates and cocaine in oral fluid. Oral fluid samples were collected using the Cozart<sup>®</sup> RapiScan collection system from 358 donors who were receiving treatment for their addiction and were monitored for drug misuse. A further 103 oral fluid samples were collected from volunteer donors who were not drug users. The samples were analyzed in the laboratory using the two-panel Cozart<sup>®</sup> RapiScan cartridge for opiates and cocaine and confirmed using gas chromatography–mass spectrometry (GC–MS). The samples were stored frozen at −20 °C until analysis by GC–MS. The overall accuracy of the CRS for both opiates and cocaine was 100%. Samples spiked at 50% above and below the cut-off consistently gave negative and positive results respectively. A total of 88 samples were positive for various opiates and 111 samples were positive for cocaine and/or its metabolites. The CRS for opiates and cocaine in oral fluid, using a cut-off of 30 ng/mL morphine or benzoylecgonine equivalents in neat oral fluid, had overall efficiencies of 98% and 99%, respectively, versus GC–MS. A series of potential adulterants of oral fluid were evaluated and shown not to alter the outcome of the test result.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cooper, Dr Gail
Authors: Cooper, G., Wilson, L., Reid, C., Main, L., and Hand, C.
Subjects:R Medicine > RA Public aspects of medicine > RA1001 Forensic Medicine. Medical jurisprudence. Legal medicine
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Clinical Specialities
Journal Name:Forensic Science International
Publisher:Elsevier Ireland Ltd
ISSN:0379-0738
ISSN (Online):1872-6283
Published Online:15 April 2005

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