Enlighten
Research publications by members of the University of Glasgow
home > services > Enlighten

I.v. regional diamorphine for analgesia after foot surgery.

Serpell, M., Anderson, E., Wilson, D., and Dawson, N. (2000) I.v. regional diamorphine for analgesia after foot surgery. British Journal of Anaesthesia, 84 (1). pp. 95-96. ISSN 0007-0912

Full text not currently available from Enlighten.

Publisher's URL: http://bja.oxfordjournals.org/content/84/1/95.abstract

Abstract

Opioids administered to peripheral tissues can have significant analgesic effects in doses which would not be effective centrally. We have assessed the effects of regional diamorphine 2.5 mg i.v. in 14 patients undergoing surgical correction of bilateral arthritic foot deformities in a prospective, randomized, double-blind study. Patients acted as their own controls as only one foot received the active drug. Visual analogue scale (VAS) pain scores and wound tenderness were measured over 72 h. Diamorphine did not improve median VAS area under the curve pain scores during the first 6 h after surgery (33 (95% confidence intervals (CI) 25-46) vs 24 (17-35)). It also did not effect wound hypersensitivity when tested at 72 h after surgery (95 (47-125) vs 90 (50-125) g). There were no significant adverse effects.

Item Type:Article
Status:Published
Refereed:Yes
Glasgow Author(s):Serpell, Dr Michael
Authors: Serpell, M., Anderson, E., Wilson, D., and Dawson, N.
College/School:College of Medical Veterinary and Life Sciences > School of Medicine
Journal Name:British Journal of Anaesthesia
Publisher:Oxford University Press
ISSN:0007-0912
ISSN (Online):1471-6771

University Staff: Request a correction | Enlighten Editors: Update this record