The longitudinal relationship between the systemic inflammatory response, circulating T-lymphocytes, interleukin-6 and -10 in patients undergoing immunotherapy for metastatic renal cancer

Ramsey, S., Aitchison, M., Graham, J. and McMillan, D.C. (2008) The longitudinal relationship between the systemic inflammatory response, circulating T-lymphocytes, interleukin-6 and -10 in patients undergoing immunotherapy for metastatic renal cancer. BJU International, 102(1), pp. 125-129. (doi:10.1111/j.1464-410X.2008.07466.x)

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Publisher's URL: http://dx.doi.org/10.1111/j.1464-410X.2008.07466.x

Abstract

To examine the longitudinal relationship between the systemic inflammatory response, circulating T-lymphocyte subpopulations, interleukin-6 and -10 in patients undergoing immunotherapy for metastatic renal cancer, as the inflammation-based Glasgow Prognostic Score (GPS) provides additional prognostic information in patients with advanced renal cancer, but the basis of the relationship between the systemic inflammatory response and poorer survival is not clear, and nor is the effect of immunotherapy on related variables

Item Type:Articles
Additional Information:The definitive version is available at www.blackwell-synergy.com
Keywords:renal cancer; immunotherapy; tumour stage; grade; T-lymphocytes; C-reactive protein; albumin; interleukin; cancer-specific survival
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:McMillan, Professor Donald
Authors: Ramsey, S., Aitchison, M., Graham, J., and McMillan, D.C.
Subjects:R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
College/School:College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing > Clinical Specialities
Journal Name:BJU International
ISSN:1464-4096
Published Online:11 March 2008

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