Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells

Sirimuthu, N., Syme, C. and Cooper, J. (2011) Investigation of the stability of labelled nanoparticles for SE(R)RS measurements in cells. Chemical Communications, 47(14), pp. 4099-4101. (doi:10.1039/c0cc05723a)

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Publisher's URL: http://dx.doi.org/10.1039/c0cc05723a

Abstract

We explore the long-term stability of two different classes of labelled nanoparticles as intracellular SE(R)RS probes. Whilst chemisorbed labels gave stable responses inside cells for extended periods of time, signals from physisorbed labels could only be measured for short periods of time. These results help inform strategies for cellular imaging using vibrational spectroscopies.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Syme, Dr Christopher and Cooper, Professor Jonathan
Authors: Sirimuthu, N., Syme, C., and Cooper, J.
Subjects:Q Science > QH Natural history > QH345 Biochemistry
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Chemical Communications
ISSN:1359-7345

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