Regulation of gene expression by the RNA-binding protein Sam68 in cancer

Rajan, P., Gaughan, L., Dalgliesh, C., El-Sherif, A., Robson, C.N., Leung, H.Y. and Elliott, D.J. (2008) Regulation of gene expression by the RNA-binding protein Sam68 in cancer. Biochemical Society Transactions, 36(3), pp. 505-507. (doi:10.1042/BST0360505)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.1042/BST0360505

Abstract

Sam68 (Src-associated in mitosis 68 kDa) is the prototypical member of the STAR (signal transducer and activator of RNA) family of RNA-binding proteins. Sam68 is implicated in a number of cellular processes including signal transduction, transcription, RNA metabolism, cell cycle regulation and apoptosis. In the present review, we summarize the functions of Sam68 as a transcriptional and post-transcriptional regulator of gene expression, with particular relevance to cancer.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Leung, Professor Hing and Rajan, Dr Prabhakar
Authors: Rajan, P., Gaughan, L., Dalgliesh, C., El-Sherif, A., Robson, C.N., Leung, H.Y., and Elliott, D.J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Biochemical Society Transactions
ISSN:0300-5127

University Staff: Request a correction | Enlighten Editors: Update this record