Gottlieb, E. (2011) p53 guards the metabolic pathway less travelled. Nature Cell Biology, 13(3), pp. 195-197. (doi: 10.1038/ncb2177)
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Publisher's URL: http://dx.doi.org/10.1038/ncb2177
Abstract
Glucose is an important source of energy and carbon, and is required for cell growth. As such, glucose utilization is increased in rapidly dividing cancer cells. The tumour suppressor p53 has now been reported to block a metabolic pathway (the pentose phosphate pathway) that diverts glucose away from bioenergetic into biosynthetic routes
| Item Type: | Articles (Editorial) |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Gottlieb, Professor Eyal |
| Authors: | Gottlieb, E. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Nature Cell Biology |
| ISSN: | 1465-7392 |
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