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Publisher's URL: http://dx.doi.org/10.1099/00221287-11-1-94
Roper's (1952) technique for the isolation in filamentous fungi of strains carrying in their hyphae diploid nuclei heterozygous for known markers has been applied with minor modifications to a third species: Penicillium chrysogenum. One of these modifications is the use of ‘dwarf’ (stunted growth) mutants for growing balanced heterokaryons. Heterozygous diploid strains of P. chrysogenum behave like those of the other two species in yielding, vegetatively, new strains with recombined properties. This behaviour can be marshalled for the deliberate breeding of improved industrial strains.
|Additional Information:||Guido Pontecorvo (1907-1999) was the University of Glasgow's first Professor of Genetics, a post that he held from 1955 to 1968.|
|Authors:||Pontecorvo, G., and Sermonti, G.|
|College/School:||College of Medical Veterinary and Life Sciences > School of Life Sciences > Life Sciences Biomolecular Science|
|Journal Name:||Journal of General Microbiology|
|Publisher:||Society for General Microbiology|