van de Sande, M. G. H. et al. (2011) Evaluating antirheumatic treatments using synovial biopsy: a recommendation for standardisation to be used in clinical trials. Annals of the Rheumatic Diseases, 70(3), pp. 423-427. (doi: 10.1136/ard.2010.139550) (PMID:21109518)
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Abstract
Inflammation of synovium is one of the hallmarks of rheumatoid arthritis (RA). Analysis of synovial tissue has increased our understanding of RA pathogenesis, aided in identifying potential therapeutic targets and has been used in the response and mechanistic evaluation of antirheumatic treatments. In addition, studies are ongoing, aimed at the identification of diagnostic and prognostic biomarkers in the synovium. This paper outlines the currently used procedures for sampling and processing of synovial tissue, and presents a standardised recommendation to support multicentre translational research
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | McInnes, Professor Iain |
Authors: | van de Sande, M. G. H., Gerlag, D. M., Lodde, B. M., van Baarsen, L. G. M., Alivernini, S., Codullo, V., Felea, I., Vieira-Sousa, E., Fearon, U., Reece, R., Montecucco, C., Veale, D. J., Pitzalis, C., Emery, P., Klareskog, L., McInnes, I.B., and Tak, P. P. |
College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
Journal Name: | Annals of the Rheumatic Diseases |
ISSN: | 0003-4967 |
Published Online: | 24 November 2010 |
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