Geissmann, F., Gordon, S., Hume, D.A., Mowat, A.M. and Randolph, G.J. (2010) Unravelling mononuclear phagocyte heterogeneity. Nature Reviews Immunology, 10(6), pp. 453-460. (doi: 10.1038/nri2784)
Full text not currently available from Enlighten.
Publisher's URL: http://dx.doi.org/10.1038/nri2784
Abstract
When Ralph Steinman and Zanvil Cohn first described dendritic cells (DCs) in 1973 it took many years to convince the immunology community that these cells were truly distinct from macrophages. Almost four decades later, the DC is regarded as the key initiator of adaptive immune responses; however, distinguishing DCs from macrophages still leads to confusion and debate in the field. Here, Nature Reviews Immunology asks five experts to discuss the issue of heterogeneity in the mononuclear phagocyte system and to give their opinion on the importance of defining these cells for future research.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Mowat, Professor Allan |
| Authors: | Geissmann, F., Gordon, S., Hume, D.A., Mowat, A.M., and Randolph, G.J. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Nature Reviews Immunology |
| ISSN: | 1474-1733 |
University Staff: Request a correction | Enlighten Editors: Update this record
Deposit and Record Details
Deposit and Record Details