The Caffeine Breath Test and CYP1A2 Activity in Children

Webster, E., McIntyre, J., Choonara, I. and Preston, T. (2004) The Caffeine Breath Test and CYP1A2 Activity in Children. Paediatric and Perinatal Drug Therapy, 5(1), pp. 28-33.

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Abstract

The caffeine breath test is a non-invasive method of studying CYP1A2 activity that is suitable for children from the ages of 3 years upwards. It involves the oral administration of a stable isotope and the collection of breath samples for a period of 2 hours. Breath samples are analysed by continuous flow isotope ratio mass spectrometry. It has been used to study both drug interactions and the effect of disease on drug metabolism.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Preston, Professor Thomas
Authors: Webster, E., McIntyre, J., Choonara, I., and Preston, T.
Subjects:R Medicine > RJ Pediatrics
College/School:College of Science and Engineering > Scottish Universities Environmental Research Centre
Journal Name:Paediatric and Perinatal Drug Therapy
Publisher:LibraPharm
ISSN:1463-0095

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