Hetero‐Oligomerization of Chemokine Receptors

Appelbe, S. and Milligan, G. (2009) Hetero‐Oligomerization of Chemokine Receptors. In: Chemokines, Part B. Series: Methods in Enzymology., 461. Academic Press, pp. 207-225. ISBN 9780123749079 (doi: 10.1016/S0076-6879(09)05410-X)

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Publisher's URL: http://dx.doi.org/10.1016/S0076-6879(09)05410-X


Although traditionally assumed to be monomeric signaling units, G[hyphen (true graphic)]protein-coupled receptors (GPCRs) have been shown to exist as dimers/oligomers. Many chemokine receptors have been demonstrated to form homo[hyphen (true graphic)]oligomers, and hetero[hyphen (true graphic)]oligomerization between both pairs of chemokine receptors and chemokine receptors and other GPCRs has also been demonstrated. This chapter highlights some of the most common techniques used to investigate chemokine receptor oligomerization

Item Type:Book Sections
Glasgow Author(s) Enlighten ID:Appelbe, Mrs Shirley and Milligan, Professor Graeme
Authors: Appelbe, S., and Milligan, G.
College/School:College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience
Publisher:Academic Press
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