Nonstimulated early visual areas carry information about surrounding context

Smith, F.W. and Muckli, L. (2010) Nonstimulated early visual areas carry information about surrounding context. Proceedings of the National Academy of Sciences of the United States of America, 107(46), pp. 20099-20103. (doi: 10.1073/pnas.1000233107) (PMID:21041652) (PMCID:PMC2993348)

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Abstract

Even within the early sensory areas, the majority of the input to any given cortical neuron comes from other cortical neurons. To extend our knowledge of the contextual information that is transmitted by such lateral and feedback connections, we investigated how visually nonstimulated regions in primary visual cortex (V1) and visual area V2 are influenced by the surrounding context. We used functional magnetic resonance imaging (fMRI) and pattern-classification methods to show that the cortical representation of a nonstimulated quarter-field carries information that can discriminate the surrounding visual context. We show further that the activity patterns in these regions are significantly related to those observed with feed-forward stimulation and that these effects are driven primarily by V1. These results thus demonstrate that visual context strongly influences early visual areas even in the absence of differential feed-forward thalamic stimulation.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Muckli, Professor Lars and Smith, Dr Fraser
Authors: Smith, F.W., and Muckli, L.
Subjects:B Philosophy. Psychology. Religion > BF Psychology
College/School:College of Medical Veterinary and Life Sciences > Institute of Neuroscience and Psychology
College of Science and Engineering > School of Psychology
Journal Name:Proceedings of the National Academy of Sciences of the United States of America
Publisher:National Academy of Sciences of the United States of America
ISSN:0027-8424
ISSN (Online):1091-6490
Published Online:01 November 2010
Copyright Holders:Copyright © 2010 National Academy of Sciences of the United States of America
First Published:First published in Proceedings of the National Academy of Sciences of the United States of America 107(46):20099-20103
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
474481Brain processes predicting forthcoming perception - cortical feedback and visual predictionsLars MuckliBiotechnology and Biological Sciences Research Council (BBSRC)BB/G005044/1Cognitive Neuroimaging & Neuroengineering Technologies