Phononic crystal structures for acoustically driven microfluidic manipulations

Wilson, R. , Reboud, J. , Bourquin, Y., Neale, S. , Zhang, Y. and Cooper, J. (2011) Phononic crystal structures for acoustically driven microfluidic manipulations. Lab on a Chip, 11(2), pp. 323-328. (doi:10.1039/C0LC00234H)

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Abstract

The development of microfluidic systems is often constrained both by difficulties associated with the chip interconnection to other instruments and by limitations imposed by the mechanisms that can enable fluid movement and processing. Surface acoustic wave (SAW) devices have shown promise in allowing samples to be manipulated, although designing complex fluid operations involves using multiple electrode transducers. We now demonstrate a simple interface between a piezoelectric SAW device and a disposable microfluidic chip, patterned with phononic structures to control the acoustic wave propagation. The surface wave is coupled from the piezoelectric substrate into the disposable chip where it interacts with the phononic lattice. By implementing both a phononic filter and an acoustic waveguide, we illustrate the potential of the technique by demonstrating microcentrifugation for particle and cell concentration in microlitre droplets. We show for the first time that the interaction of the fluid within this metamaterial phononic lattice is dependent upon the frequency of the acoustic wave, providing a route to programme complex fluidic functions into a microchip (in much the same way, by analogy, that a holographic element would change the phase of a light wave in optical tweezers). A practical realisation of this involves the centrifugation of blood on the chip.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Wilson, Dr Robert and Cooper, Professor Jonathan and Reboud, Dr Julien and Zhang, Mr Yi and Neale, Dr Steven
Authors: Wilson, R., Reboud, J., Bourquin, Y., Neale, S., Zhang, Y., and Cooper, J.
College/School:College of Science and Engineering > School of Engineering > Biomedical Engineering
College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
Journal Name:Lab on a Chip
Publisher:Royal Society of Chemistry
ISSN:1473-0197
ISSN (Online):1473-0189
Published Online:08 November 2010

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