SERS mapping of nanoparticle labels in single cells using a microfluidic chip

Syme, C.D., Sirimuthu, N.M.S., Faley, S.L. and Cooper, J. (2010) SERS mapping of nanoparticle labels in single cells using a microfluidic chip. Chemical Communications, 46(42), pp. 7921-7923. (doi:10.1039/C0CC02209H)

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Publisher's URL: http://dx.doi.org/10.1039/C0CC02209H

Abstract

We report for the first time the time-resolved mapping of intracellular nanoparticle labels from within living cells retained in a microstructured trap using Raman spectroscopy. The methods employed here also demonstrate the ability to rapidly discriminate between cell populations containing different SERS labels.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Faley, Dr Shannon and Syme, Dr Christopher and Cooper, Professor Jonathan
Authors: Syme, C.D., Sirimuthu, N.M.S., Faley, S.L., and Cooper, J.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Chemical Communications
Publisher:Royal Society of Chemistry
ISSN:1359-7345
ISSN (Online):1364-548X
Published Online:21 September 2010

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