Gilbert, D., Heiner, M., Rosser, S., Fulton, R., Gu, X. and Trybilo, M. (2008) A case study in model-driven synthetic biology. International Federation for Information Processing, 268 (B, pp. 163-175. (doi: 10.1007/978-0-387-09655-1_15)
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Abstract
We report on a case study in synthetic biology, demonstrating the model-driven design of a self-powering electrochemical biosensor. An essential result of the design process is a general template of a biosensor, which can be instantiated to be adapted to specific pollutants. This template represents a gene expression network extended by metabolic activity. We illustrate the model-based analysis of this template using qualitative, stochastic and continuous Petri nets and related analysis techniques, contributing to a reliable and robust design.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Rosser, Professor Susan and Macisaac, Dr Rachael and Gilbert, Prof David |
| Authors: | Gilbert, D., Heiner, M., Rosser, S., Fulton, R., Gu, X., and Trybilo, M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Molecular Biosciences College of Science and Engineering > School of Computing Science |
| Journal Name: | International Federation for Information Processing |
| ISSN: | 1571-5736 |
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