Bioactive polychlorinated bibenzyls from the liverwort Riccardia polyclada

Labbé, C., Faini, F., Villagrán, C., Coll, J. and Rycroft, D.S. (2007) Bioactive polychlorinated bibenzyls from the liverwort Riccardia polyclada. Journal of Natural Products, 70(12), pp. 2019-2021. (doi: 10.1021/np070192c)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.1021/np070192c

Abstract

GC-MS and <sup>1</sup>H NMR spectroscopic profiling of a CDCl<sub>3</sub> extract of the liverwort <i>Riccardia polyclada</i> (syn. <i>R. umbrosa</i>) revealed the presence of four main compounds bearing several chlorine atoms on a bibenzyl skeleton. Separation of a CH<sub>2</sub>Cl<sub>2</sub> extract was achieved using preparative TLC, and structures <b>1</b>–<b>4</b> were proposed on the basis of spectroscopic evidence. Compounds <b>1</b>–<b>4</b> were active in a brine shrimp lethality bioassay (<i>Artemia salina</i>). In addition, <b>2</b> and <b>4</b> displayed moderate antifeedant activity in disk-choice bioassays with <i>Spodoptera littoralis</i> larvae and inhibited the growth of <i>Cladosporium herbarum</i> cultures on TLC plates.

Item Type:Articles
Keywords:phytochemistry, Chile
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Rycroft, Dr David
Authors: Labbé, C., Faini, F., Villagrán, C., Coll, J., and Rycroft, D.S.
Subjects:Q Science > QD Chemistry
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Journal of Natural Products
ISSN:0163-3864

University Staff: Request a correction | Enlighten Editors: Update this record