Labbé, C., Faini, F., Villagrán, C., Coll, J. and Rycroft, D.S. (2007) Bioactive polychlorinated bibenzyls from the liverwort Riccardia polyclada. Journal of Natural Products, 70(12), pp. 2019-2021. (doi: 10.1021/np070192c)
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Publisher's URL: http://dx.doi.org/10.1021/np070192c
Abstract
GC-MS and <sup>1</sup>H NMR spectroscopic profiling of a CDCl<sub>3</sub> extract of the liverwort <i>Riccardia polyclada</i> (syn. <i>R. umbrosa</i>) revealed the presence of four main compounds bearing several chlorine atoms on a bibenzyl skeleton. Separation of a CH<sub>2</sub>Cl<sub>2</sub> extract was achieved using preparative TLC, and structures <b>1</b>–<b>4</b> were proposed on the basis of spectroscopic evidence. Compounds <b>1</b>–<b>4</b> were active in a brine shrimp lethality bioassay (<i>Artemia salina</i>). In addition, <b>2</b> and <b>4</b> displayed moderate antifeedant activity in disk-choice bioassays with <i>Spodoptera littoralis</i> larvae and inhibited the growth of <i>Cladosporium herbarum</i> cultures on TLC plates.
Item Type: | Articles |
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Keywords: | phytochemistry, Chile |
Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Rycroft, Dr David |
Authors: | Labbé, C., Faini, F., Villagrán, C., Coll, J., and Rycroft, D.S. |
Subjects: | Q Science > QD Chemistry |
College/School: | College of Science and Engineering > School of Chemistry |
Journal Name: | Journal of Natural Products |
ISSN: | 0163-3864 |
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