Rixon, F.J. (2008) A good catch: packaging the virus genome. Cell Host and Microbe, 3(3), pp. 120-122. (doi: 10.1016/j.chom.2008.02.009) (PMID:18329609)
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Abstract
In tailed bacteriophages and herpesviruses, double-stranded DNA is packaged into a pre-existing protein shell, through a dedicated channel known as the portal. In a recent issue of Molecular Cell, Zheng et al. determined the structure of the bacteriophage P22 portal complex in pre- and postpackaging conformations, identifying structural changes that serve to retain the genome within the virus particle and prime it for injection into a new host.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Rixon, Dr Frazer |
| Authors: | Rixon, F.J. |
| Subjects: | Q Science > QH Natural history > QH426 Genetics |
| College/School: | College of Medical Veterinary and Life Sciences > School of Life Sciences |
| Journal Name: | Cell Host and Microbe |
| Publisher: | Cell Press |
| ISSN: | 1931-3128 |
| ISSN (Online): | 1934-6069 |
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