Todd, A.J. (2010) Neuronal circuitry for pain processing in the dorsal horn. Nature Reviews Neuroscience, 11(12), pp. 823-836. (doi: 10.1038/nrn2947)
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Abstract
Neurons in the spinal dorsal horn process sensory information, which is then transmitted to several brain regions, including those responsible for pain perception. The dorsal horn provides numerous potential targets for the development of novel analgesics and is thought to undergo changes that contribute to the exaggerated pain felt after nerve injury and inflammation. Despite its obvious importance, we still know little about the neuronal circuits that process sensory information, mainly because of the heterogeneity of the various neuronal components that make up these circuits. Recent studies have begun to shed light on the neuronal organization and circuitry of this complex region.
Item Type: | Articles |
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Status: | Published |
Refereed: | Yes |
Glasgow Author(s) Enlighten ID: | Todd, Professor Andrew |
Authors: | Todd, A.J. |
Subjects: | R Medicine > RC Internal medicine > RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry |
College/School: | College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience |
Journal Name: | Nature Reviews Neuroscience |
Publisher: | Nature Publishing Group |
ISSN: | 1471-003X |
ISSN (Online): | 1471-0048 |
Published Online: | 11 November 2010 |
Copyright Holders: | Copyright © 2010 Macmillan Publishers |
First Published: | First published in Nature Reviews Neuroscience 11(12):823-836 |
Publisher Policy: | Reproduced in accordance with the copyright policy of the publisher |
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