Imaging T-cell movement in the brain during experimental cerebral malaria

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi:10.1111/j.1365-3024.2008.01090.x)

Ortolano, F. et al. (2009) Imaging T-cell movement in the brain during experimental cerebral malaria. Parasite Immunology, 31(3), 147-150 (4). (doi:10.1111/j.1365-3024.2008.01090.x)

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Abstract

T-cells are known to play a role in the pathology associated with experimental cerebral malaria, although it has not previously been possible to examine their behaviour in brain. Using multiphoton laser scanning microscopy, we have examined the migration and movement of these cells in brain tissue. We believe that this approach will help define host-parasite interactions and examine how intervening in these relationships affects the development of cerebral pathology

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Maffia, Dr Pasquale and Carswell, Dr Hilary and Millington, Dr Owain and Brewer, Professor James and Garside, Professor Paul and Benson, Dr Robert and Hutchison, Dr Sharon and Dever, Dr Gary
Authors: Ortolano, F., Maffia, P., Dever, G., Hutchison, S., Benson, R., Millington, O.R., De Simoni, M., Bushell, T.J., Garside, P., Carswell, H., and Brewer, J.
Subjects:R Medicine > RC Internal medicine
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Parasite Immunology
Journal Abbr.:Parasite Immunol.
Publisher:Wiley-Blackwell Publishing Ltd.
ISSN:0141-9838
ISSN (Online):1365-3024
Published Online:03 December 2008

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