Ring-closing metathesis in the synthesis of BC ring-systems of taxol

Ma, C., Schlitz, S., Le Goff, X. and Prunet, J. (2008) Ring-closing metathesis in the synthesis of BC ring-systems of taxol. Chemistry: A European Journal, 14(24), pp. 7314-7323. (doi: 10.1002/chem.200800774)

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Abstract

BC ring-systems of taxol with different or no protecting group for the C1,C2-diol moiety have been efficiently synthesized. The eight-membered B ring is formed by a ring-closing metathesis reaction (RCM) between the C10 and C11 carbon atoms. The influence of the 1,2-diol protecting group on the RCM reaction has been studied in detail

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Prunet, Dr Joelle
Authors: Ma, C., Schlitz, S., Le Goff, X., and Prunet, J.
Subjects:Q Science > QD Chemistry
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Chemistry: A European Journal
Journal Abbr.:Chem. Eur J.
ISSN:0947-6539
ISSN (Online):1521-3765
Published Online:04 July 2008

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