Kinetics, dose-response, excretion, and toxicity of methylmercury in free-living Cory's shearwater chicks

Monteiro, L.R. and Furness, R.W. (2001) Kinetics, dose-response, excretion, and toxicity of methylmercury in free-living Cory's shearwater chicks. Environmental Toxicology and Chemistry, 20(8), pp. 1816-1823. (doi:10.1897/1551-5028(2001)020<1816:KDREAT>2.0.CO;2)

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Publisher's URL: http://dx.doi.org/10.1897/1551-5028(2001)020<1816:KDREAT>2.0.CO;2

Abstract

Methylmercury (MHg) kinetics, dose-response, excretion, and toxicity were experimentally evaluated and compared between small tone to two weeks old) and large (six to seven weeks old), free-living Gory's shearwater chicks. The half-time for the terminal elimination phase of MHg in blood (5.7 d) and the average percentage of ingested MI-Ig deposited in the blood volume (12%) were independent of the age at exposure. Therefore, these data were employed to derive a relationship between steady-state blood concentrations and dietary intake of MHg in bird chicks. Plumage:blood ratios were independent of dose and could be used as partition coefficients. Dose-response relationships in plumage and blood were linear over the wide range of exposures employed. Blood dose-responses of MHg in small and large chicks were similar. Excretion percentages into the final plumage varied between 42 and 60% of intake. The body condition of experimental chicks did not indicate sublethal toxicity of the doses administered; hence, the exposure levels provide maximum avian no-observed-adverse-effect levels for external symptoms in wild seabird chicks

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Furness, Professor Robert
Authors: Monteiro, L.R., and Furness, R.W.
Subjects:Q Science > QL Zoology
G Geography. Anthropology. Recreation > GE Environmental Sciences
College/School:College of Medical Veterinary and Life Sciences > Institute of Biodiversity Animal Health and Comparative Medicine
Journal Name:Environmental Toxicology and Chemistry
ISSN:0730-7268

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