Time spent at home poststroke: “home-time” a meaningful and robust outcome measure for stroke trials

Quinn, T.J. , Dawson, J. , Lees, J.S. , Chang, T.P., Walters, M.R. and Lees, K.R. (2008) Time spent at home poststroke: “home-time” a meaningful and robust outcome measure for stroke trials. Stroke, 39(1), pp. 231-233. (doi:10.1161/STROKEAHA.107.493320)

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Publisher's URL: http://dx.doi.org/10.1161/STROKEAHA.107.493320

Abstract

<p><b>Background and Purpose:</b> Stroke outcome assessment requires some measure of functional recovery. Several instruments are in common use but all have recognized limitations. We examined duration of stay in the patient’s own home over the first 90 days since stroke—"home-time"—as an alternative outcome likely to show graded response with improved reliability.</p> <p><b>Methods:</b> We examined prospectively collected data from the GAIN International trial using analysis of variance with Bonferroni contrasts of adjacent modified Rankin scale score categories.</p> <p><b>Results:</b> We had full outcome data from 1717 of 1788 patients. Increasing home-time was associated with improved modified Rankin scale scores (P<0.0001). The relationship held across all modified Rankin scale grades except 4 to 5.</p> <p><b>Conclusions:</b> Home-time offers a robust, useful, and easily validated outcome measure for stroke, particularly across better recovery levels.</p>

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Quinn, Dr Terence and Lees, Professor Kennedy and Dawson, Professor Jesse and Lees, Jennifer and Walters, Professor Matthew
Authors: Quinn, T.J., Dawson, J., Lees, J.S., Chang, T.P., Walters, M.R., and Lees, K.R.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Journal Name:Stroke
Publisher:American Heart Association
ISSN:0039-2499
ISSN (Online):1524-4628
Published Online:21 November 2007
Copyright Holders:Copyright © 2008 American Heart Association
First Published:First published in Stroke 39(1):231-233
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher

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