Cell-Penetrating Peptide TP10 Shows Broad-Spectrum Activity against both Plasmodium falciparum and Trypanosoma brucei brucei

Arrighi, R. B. G., Ebikeme, C., Jiang, Y., Ranford-Cartwright, L.C., Barrett, M.P., Langel, U. and Faye, I. (2008) Cell-Penetrating Peptide TP10 Shows Broad-Spectrum Activity against both Plasmodium falciparum and Trypanosoma brucei brucei. Antimicrobial Agents and Chemotherapy, 52(9), pp. 3414-3417. (doi:10.1128/AAC.01450-07)

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Publisher's URL: http://dx.doi.org/10.1128/AAC.01450-07

Abstract

Malaria and trypanosomiasis are diseases which afflict millions, for which novel therapies are urgently required. We have tested two well characterized cell penetrating peptides (CPPs) for anti-parasitic activity. One CPP designated TP10, has broad spectrum anti-parasitic activity against Plasmodium falciparum, both blood and mosquito stages, and blood stage Trypanosoma brucei brucei

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Ranford-Cartwright, Dr Lisa and Barrett, Professor Michael
Authors: Arrighi, R. B. G., Ebikeme, C., Jiang, Y., Ranford-Cartwright, L.C., Barrett, M.P., Langel, U., and Faye, I.
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Antimicrobial Agents and Chemotherapy
Journal Abbr.:Antimicrob Agents Chemother
Publisher:American Society for Microbiology
ISSN:0066-4804
ISSN (Online):1098-6596

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