Electrocoalescence Mechanisms of Microdroplets Using Localized Electric Fields in Microfluidic Channels

Zagnoni, M., Le Lain, G. and Cooper, J.M. (2010) Electrocoalescence Mechanisms of Microdroplets Using Localized Electric Fields in Microfluidic Channels. Langmuir, 26(18), pp. 14443-14449. (doi:10.1021/la101517t)

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Abstract

Electrocoalescence of water-in-oil microdroplets in microfluidic channels is an active technique that enables dioplet-based mixing functionalities to be achieved in lab-on-a-chip applications In this work, a characterization of the electrocoalescence mechanisms of water microdroplets in oil is presented, using localized electric field systems We report a theoretical and experimental description of the electrocoalscence behavior of droplet pairs by varying the physical and fluid dynamic conditions of the phases Our results demonstrate that localized electric field systems can be reliably used to merge droplets in pairs, regardless of the distance between the drops The coalescence behavior was dependent upon the viscosity of the continuous phase for water droplets that were separated by a thick layer of oil and upon interfacial tension for droplets that were in close proximity We showed that these systems have the potential to be used lot high-throughput applications and that, unlike other examples of active systems in the literature, the need of droplet synchronization and the application of high voltages is considerably reduced

Item Type:Articles
Keywords:channel COALESCENCE DIELECTROPHORESIS DNA DROPLET MICROFLUIDICS EMULSION DROPLETS ENCAPSULATION fluid Lab-On-A-Chip model OIL RECTANGULAR MICROCHANNELS system water WATER DROPLETS
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cooper, Professor Jonathan and Zagnoni, Dr Michele
Authors: Zagnoni, M., Le Lain, G., and Cooper, J.M.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Langmuir
ISSN:0743-7463

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
460401Droplet-based microfluidics for single cell-omics.Jonathan CooperBiotechnology and Biological Sciences Research Council (BBSRC)BB/F005024/1Biomedical Engineering