Cardiac ageing and systemic disorders

Quinn, T.J. and Stott, D.J. (2012) Cardiac ageing and systemic disorders. In: Sinclair, A.J., Morley, J.E. and Vellas, B. (eds.) Pathy's Principle and Practice of Geriatric Medicine. Wiley-Blackwell: Chichester, UK, pp. 405-412. ISBN 9780470683934 (doi:10.1002/9781119952930.ch35)

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Abstract

Age-related changes in the anatomy (at both macroscopic and microscopic level) and physiology of the ageing heart are frequently reported. Separating intrinsic aging effects from the sequelae of concomitant disease is challenging and many of the changes classically associated with ageing may reflect underlying coronary artery and hypertensive disease. However, certain common features of an ageing heart phenotype can be described. Although ageing itself should not limit cardiac function sufficiently to provoke symptoms, the older heart has less reserve when faced with systemic upset. With this in mind the remainder of the chapter will explore relationships between cardiac function in older age and disease in other organ systems. Particular attention will be paid to the complex interplay between cerebrovascular, endocrine systems and the ageing heart.

Item Type:Book Sections
Status:Published
Glasgow Author(s) Enlighten ID:Stott J, Professor David and Quinn, Dr Terry
Authors: Quinn, T.J., and Stott, D.J.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cardiovascular and Medical Sciences
Publisher:Wiley-Blackwell
ISBN:9780470683934

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