A tal(in) of cell spreading

Frame, M. and Norman, J. (2008) A tal(in) of cell spreading. Nature Cell Biology, 10(9), pp. 1017-1019. (doi: 10.1038/ncb0908-1017)

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Publisher's URL: http://dx.doi.org/10.1038/ncb0908-1017

Abstract

Talin can activate integrins to bind the extracellular matrix and also connect matrix-engaged integrins to the actin cytoskeleton. New work shows that cell spreading can be dissected into three distinct phases according to their differential requirements for talin function.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Norman, Professor James
Authors: Frame, M., and Norman, J.
College/School:College of Medical Veterinary and Life Sciences > School of Cancer Sciences
Journal Name:Nature Cell Biology
ISSN:1465-7392

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