Frezza, C., Tennant, D.A. and Gottlieb, E. (2010) IDH1 Mutations in Gliomas: When an Enzyme Loses Its Grip. Cancer Cell, 17(1), pp. 7-9. (doi: 10.1016/j.ccr.2009.12.031)
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Publisher's URL: http://dx.doi.org/10.1016/j.ccr.2009.12.031
Abstract
The growing interest in cancer metabolism is best demonstrated by the rapid progress made in studying isocitrate dehydrogenase (IDH) mutations since their discovery just over a year ago. In a recent study published in Nature, Dang et al. identified 2-hydroxyglutarate as a product of tumor-associated IDH mutants with potential oncogenic activities.
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Frezza, Mr Christian and Tennant, Mr Daniel and Gottlieb, Professor Eyal |
| Authors: | Frezza, C., Tennant, D.A., and Gottlieb, E. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Cancer Sciences |
| Journal Name: | Cancer Cell |
| ISSN: | 15356108 |
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