A role for Numb in p53 stabilization

Carter, S. and Vousden, K. (2008) A role for Numb in p53 stabilization. Genome Biology, 9(5), p. 221. (doi:10.1186/gb-2008-9-5-221)

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Publisher's URL: http://dx.doi.org/10.1186/gb-2008-9-5-221


The cell-fate determinant Numb has recently been shown to help activate the tumor suppressor protein p53. Loss of Numb in breast cancers would result, therefore, in both the activation of the potential oncogene Notch and the diminution of tumor suppression by p53

Item Type:Articles
Glasgow Author(s) Enlighten ID:Vousden, Karen and Carter, Dr Stephanie
Authors: Carter, S., and Vousden, K.
College/School:College of Medical Veterinary and Life Sciences > Institute of Cancer Sciences
Journal Name:Genome Biology

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