One-pot synthesis of dihydroimidazo- and imidazophenanthridinium salts

Parenty, A. D. C. and Cronin, L. (2008) One-pot synthesis of dihydroimidazo- and imidazophenanthridinium salts. Synthesis(1), pp. 155-160. (doi:10.1055/s-2007-983895)

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Abstract

Two highly efficient and general one-pot annulation reactions are described for the synthesis of dihydroimidazo- and imidazophenanthridinium salts (DIPs(+) and IPs(+)). These two methodologies exploit the difference in reactivity between primary amino-based or ammonia nucleophiles and the dielectrophilic starting material, 2-bromoethylphenanthridinium bromide.

Item Type:Articles
Keywords:Ammonia annulation annulation reaction anticancer agents BROMIDE DIFFERENCE DNA intercalating agents DNA-BINDING AGENTS DUPLEX DNA EFFICIENT HETEROCYCLES MOLECULES ONE-POT phenanthridinium derivatives PLATINUM PHENANTHRIDINIUM COMPLEXES REACTIVITY RING SALT
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Parenty, Mr Alexis and Cronin, Professor Lee
Authors: Parenty, A. D. C., and Cronin, L.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Synthesis
ISSN:0039-7881
ISSN (Online):1437-210X

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