Chemistry and the missing era of evolution

Cairns-Smith, A. G. (2008) Chemistry and the missing era of evolution. Chemistry: A European Journal, 14(13), pp. 3830-3839. (doi: 10.1002/chem.200701215 Univ Glasgow, Dept Chem, Glasgow G12 8QQ, Lanark, Scotland.)

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Abstract

The Darwinian evolution of life on earth depends utterly on complex molecular machinery, which, it seems, could only have arisen through a Darwinian evolution. The "RNA world" idea reduces this paradox, but requires a geochemically implausible supply of RNA monomers. A pre-RNA era of natural selection is implied. I suggest that originally this was based on inorganic materials that came to replicate permutations with specific (e.g. catalytic) effects.

Item Type:Articles
Keywords:chemical biology CHEMISTRY COMPLEX COMPLEXES crystal growth DIHYDROFOLATE-REDUCTASE DIRECTED EVOLUTION DYNAMICS ENZYME CATALYSIS enzymes EVOLUTION HYPOTHESIS inorganic chemistry LIFE MINERALS MOLECULE NUCLEIC-ACIDS ORIGIN RNA WORLD SELECTION
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cairns-Smith, Dr Graham
Authors: Cairns-Smith, A. G.
College/School:College of Science and Engineering > School of Chemistry
Journal Name:Chemistry: A European Journal
Journal Abbr.:Chem. Eur J.
ISSN:0947-6539
ISSN (Online):1521-3765

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