Challenges of treating asthma in people who smoke

Spears, M., Cameron, E., Chaudhuri, R. and Thomson, N.C. (2010) Challenges of treating asthma in people who smoke. Expert Review of Clinical Immunology, 6(2), pp. 257-268. (doi: 10.1586/ECI.09.85)

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Abstract

Cigarette smoking is common in asthma and is associated with poor symptom control and a reduced therapeutic response to inhaled and oral corticosteroids as compared with nonsmokers with asthma. This review examines the range of adverse health effects of smoking in asthma, the inflammatory mechanisms that may influence the efficacy of current drugs and discusses potential future therapeutic directions

Item Type:Articles
Keywords:AIRWAY INFLAMMATION allergy ALVEOLAR MACROPHAGES ASTHMA CARE CIGARETTE-SMOKING combination therapy corticosteroid corticosteroid insensitivity HEALTH HISTONE DEACETYLASE leukotriene-receptor antagonist LUNG-FUNCTION MECHANISM MILD ASTHMA MUSCLE OBSTRUCTIVE PULMONARY-DISEASE PEOPLE RANDOMIZED CLINICAL-TRIALS Scotland SEVERE PERSISTENT ASTHMA smoker SMOKING smoking cessation theophylline TRANSDERMAL NICOTINE
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Thomson, Professor Neil and Cameron, Dr Euan and Spears, Dr Mark and Chaudhuri, Dr Rekha
Authors: Spears, M., Cameron, E., Chaudhuri, R., and Thomson, N.C.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
College of Medical Veterinary and Life Sciences > School of Medicine, Dentistry & Nursing
Journal Name:Expert Review of Clinical Immunology
ISSN:1744-666X

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