Arendt, M., Nasir, L. and Morgan, I.M. (2009) Oncolytic gene therapy for canine cancers: teaching old dog viruses new tricks. Veterinary and Comparative Oncology, 7(3), pp. 153-161. (doi: 10.1111/j.1476-5829.2009.00187.x)
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Abstract
The use of viruses to treat cancer has been studied for decades. With the advancement of molecular biology, viruses have been modified and genetically engineered to optimize their ability to target cancer cells. Canine viruses, such as distemper virus and adenovirus, are being exploited for the treatment of canine cancer as the dog has proven to be a good comparative model for human cancer research and proof of concept investigations. In this review, we introduce the concept of oncolytic viruses and describe some of the preliminary attempts to use oncolytic viruses for the treatment of canine cancer
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Morgan, Professor Iain and Nasir, Professor Lubna and Arendt, Ms Maja |
| Authors: | Arendt, M., Nasir, L., and Morgan, I.M. |
| College/School: | College of Medical Veterinary and Life Sciences > School of Biodiversity, One Health & Veterinary Medicine College of Medical Veterinary and Life Sciences > School of Infection & Immunity |
| Journal Name: | Veterinary and Comparative Oncology |
| ISSN: | 1476-5810 |
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