Campo, M.S. and Roden, R.B.S. (2010) Papillomavirus Prophylactic Vaccines: Established Successes, New Approaches. Journal of Virology, 84(3), pp. 1214-1220. (doi: 10.1128/JVI.01927-09)
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Abstract
Vaccines against the human papillomaviruses (HPVs) most frequently associated with cancer of the cervix are now available. These prophylactic vaccines, based on virus-like particles (VLPs), are extremely effective, providing protection from infection in almost 100% of cases. However, the vaccines present some limitations: they are effective primarily against the HPV type present in the vaccine, are expensive to produce, and need a cold chain. Vaccines based on the minor capsid protein L2 have been very successful in animal models and have been shown to provide a good level of protection against different papillomavirus types. The potential of L2-based vaccines to protect against many types of HPVs is discussed
| Item Type: | Articles |
|---|---|
| Status: | Published |
| Refereed: | Yes |
| Glasgow Author(s) Enlighten ID: | Campo, M Saveria |
| Authors: | Campo, M.S., and Roden, R.B.S. |
| College/School: | College of Medical Veterinary and Life Sciences |
| Journal Name: | Journal of Virology |
| ISSN: | 0022-538X |
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