Use of magnetic resonance imaging for morphometric analysis of the caudal cranial fossa in Cavalier King Charles Spaniels

Carrera, I., Dennis, R., Mellor, D.J. , Penderis, J. and Sullivan, M. (2009) Use of magnetic resonance imaging for morphometric analysis of the caudal cranial fossa in Cavalier King Charles Spaniels. American Journal of Veterinary Research, 70(3), pp. 340-345. (doi:10.2460/ajvr.70.3.340)

Carrera, I., Dennis, R., Mellor, D.J. , Penderis, J. and Sullivan, M. (2009) Use of magnetic resonance imaging for morphometric analysis of the caudal cranial fossa in Cavalier King Charles Spaniels. American Journal of Veterinary Research, 70(3), pp. 340-345. (doi:10.2460/ajvr.70.3.340)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.2460/ajvr.70.3.340

Abstract

Objective-To perform morphometric analysis of the caudal cranial fossa in Cavalier King Charles Spaniels (CKCSs), to assess the relationship between caudal fossa dimensions and the frequency of magnetic resonance imaging (MRI) features of occipital abnormalities in CKCSs (with and without syringomyelia), and to compare caudal cranial fossa measurements in CKCSs with measurements of 2 groups of mesaticephalic dogs. Animals-70 CKCSs and 80 mesaticephalic (control) dogs. Procedures-Dogs were placed into 4 groups as follows: Labrador Retrievers (n = 40), spaniel-type dogs (40; English Springer Spaniels and Cocker Spaniels), CKCSs with syringomyelia (55), and CKCSs without syringomyelia (15). Multiple morphometric measurements (linear, angular, and area) were obtained from cranial midsagittal T2-weighted magnetic resonance images including the brain and cervical portion of the spinal cord. Several specific MRI findings were also recorded for CKCSs that appeared to affect the occipital bone and cervicomedullary junction. Results-No significant difference was identified among breeds in control groups and between sexes in any of the groups for all morphometric measurements. Significant differences were identified in CKCSs, compared with mesaticephalic dogs, in the area of the caudal cranial fossa and for several linear measurements that reflected the length of the ventral aspect of the occipital bone. These differences were greater in CKCSs with syringomyelia. All CKCSs had abnormalities in occipital bone shape. Conclusions and Clinical Relevance-CKCSs had a shallower caudal cranial fossa and abnormalities of the occipital bone, compared with those of mesaticephalic dogs. These changes were more severe in CKCSs with syringomyelia. (Am J Vet Res 2009;70:340345)

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Penderis, Professor Jacques and Sullivan, Professor Martin and Carrera, Miss Inez and Mellor, Professor Dominic
Authors: Carrera, I., Dennis, R., Mellor, D.J., Penderis, J., and Sullivan, M.
College/School:College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
Journal Name:American Journal of Veterinary Research
Publisher:American Veterinary Medical Association
ISSN:0002-9645
ISSN (Online):1943-5681

University Staff: Request a correction | Enlighten Editors: Update this record