Microrheology with optical tweezers

Yao, A., Tassieri, M. , Padgett, M. and Cooper, J. (2009) Microrheology with optical tweezers. Lab on a Chip, 9(17), pp. 2568-2575. (doi: 10.1039/b907992k)

Abstract

Microrheology is the study of the flow of materials over small scales. It is of particular interest to those involved with investigations of fluid properties within Lab-on-a-Chip structures or within other micron-scale environments. The article briefly reviews existing active and passive methods used in the study of fluids. It then explores in greater detail the use of optical tweezers as an emerging method to investigate rheological phenomena, including, for example, viscosity and viscoelasticity, as well as the related topic of flow. The article also describes, briefly, potential future applications of this topic, in the fields of biological measurement, in general, and Lab-on-a-Chip, in particular.

• Item Type: Articles
• Keywords: Angular-momentum, biological cells, chip, complex fluids, computer-generated holograms, diffusing-wave spectroscopy, England, fields, fluid, force microscopy, lab-on-a-chip, living cells, local viscosity, particles, radiation pressure, science, tweezers
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Padgett, Professor Miles and Tassieri, Dr Manlio and Cooper, Professor Jonathan and Yao, Dr Alison
• Authors: Yao, A., Tassieri, M., Padgett, M., and Cooper, J.
• Subjects: T Technology > T Technology (General)
• College/School: College of Science and Engineering > School of Engineering > Biomedical Engineering; College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering; College of Science and Engineering > School of Physics and Astronomy
• Journal Name: Lab on a Chip
• Publisher: Royal Society of Chemistry
• ISSN: 1473-0197
• ISSN (Online): 1473-0189
• Published Online: 15 June 2009