Hysteresis in multiphase microfluidics at a T-junction

Zagnoni, M., Anderson, J. and Cooper, J.M. (2010) Hysteresis in multiphase microfluidics at a T-junction. Langmuir, 26(12), pp. 9416-9422. (doi:10.1021/la1004243)

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Abstract

Multiphase microfluidics offer a wide range of functionalities in the fields of fluid dynamics, biology, particle synthesis, and, more recently, also in logical computation. In this article, we describe the hysteresis of immiscible, multiphase flow obtained in hydrophilic, microfluidic systems at a T-junction. Stable and unstable state behaviors, in the form of segmented and parallel flow patterns of oil and water, were reliably produced, depending upon the history of the flow rates applied to the phases. The transition mechanisms between the two states were analyzed both experimentally and using numerical simulations, describing how the physical and fluid dynamic parameters influenced the hysteretic behavior of the flow. The characteristics of these multiphase systems render them suitable to be used as pressure comparators and also for the implementation of microfluidic logic operations

Item Type:Articles
Keywords:Devices, drop formation, flows, implementation, logic, microreactors, transition
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Cooper, Professor Jonathan and Zagnoni, Dr Michele
Authors: Zagnoni, M., Anderson, J., and Cooper, J.M.
College/School:College of Science and Engineering > School of Engineering > Electronics and Nanoscale Engineering
College of Science and Engineering > School of Engineering > Biomedical Engineering
Journal Name:Langmuir
ISSN:0743-7463
ISSN (Online):1520-5827
Published Online:13 May 2010

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Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
460401Droplet-based microfluidics for single cell-omics.Jonathan CooperBiotechnology and Biological Sciences Research Council (BBSRC)BB/F005024/1Biomedical Engineering