GPCR-OKB: the G protein coupled receptor oligomer knowledge base

Khelashvili, G. et al. (2010) GPCR-OKB: the G protein coupled receptor oligomer knowledge base. Bioinformatics, 26(14), pp. 1804-1805. (doi: 10.1093/bioinformatics/btq264)

Abstract

Rapid expansion of available data about G Protein Coupled Receptor (GPCR) dimers/oligomers over the past few years requires an effective system to organize this information electronically. Based on an ontology derived from a community dialog involving colleagues using experimental and computational methodologies, we developed the GPCR-Oligomerization Knowledge Base (GPCR-OKB). GPCR-OKB is a system that supports browsing and searching for GPCR oligomer data. Such data were manually derived from the literature. While focused on GPCR oligomers, GPCR-OKB is seamlessly connected to GPCRDB, facilitating the correlation of information about GPCR protomers and oligomers.

• Item Type: Articles
• Additional Information: This is a pre-copy-editing, author-produced PDF of an article accepted for publication in Bioinformatics following peer review. The definitive publisher-authenticated version [Khelashvili, G. et al. (2010) GPCR-OKB: the G protein coupled receptor oligomer knowledge base. Bioinformatics, 26 (14). pp. 1804-1805. ISSN 1367-4803] is available online at: http://dx.doi.org/10.1093/bioinformatics/btq264
• Status: Published
• Refereed: Yes
• Glasgow Author(s) Enlighten ID: Milligan, Professor Graeme
• Authors: Khelashvili, G., Dorff, K., Shan, J., Camacho-Artacho, M., Skrabanek, L., Vroling, B., Bouvier, M., Devi, L.A., George, S.R., Javitch, J.A., Lohse, M.J., Milligan, G., Neubig, R.R., Palczewski, K., Parmentier, M., Pin, J.-P., Vriend, G., Campagne, F., and Filizola, M.
• Subjects: Q Science > QH Natural history > QH345 Biochemistry
• College/School: College of Medical Veterinary and Life Sciences > School of Psychology & Neuroscience
• Journal Name: Bioinformatics
• Publisher: Oxford University Press
• ISSN: 1367-4803
• ISSN (Online): 1367-4811
• Published Online: 25 May 2010
• Copyright Holders: Copyright © 2010 Oxford University Press
• First Published: First published in Bioinformatics 26(14):1804-1805
• Publisher Policy: Reproduced in accordance with the copyright policy of the publisher