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A monoclonal antibody which blocks infection with feline immunodeficiency virus identifies a possible non-CD4 receptor

Hosie, M.J., Willett, B.J., Dunsford, T.H., Jarrett, O., and Neil, J.C. (1993) A monoclonal antibody which blocks infection with feline immunodeficiency virus identifies a possible non-CD4 receptor. Journal of Virology, 67 (3). pp. 1667-1671. ISSN 0022-538X

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Publisher's URL: http://jvi.asm.org/cgi/content/abstract/67/3/1667

Abstract

Monoclonal antibody vpg15 detects a 24-kDa cell surface protein on feline cells permissive for infection with feline immunodeficiency virus (FIV). The antibody blocks infection of FIV-susceptible cells, and expression of the vpg15 marker is decreased in FIV-infected cells in vitro. These results suggest that the antibody may recognize an FIV receptor distinct from CD4.

Item Type:Article
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Willett, Prof Brian
Authors: Hosie, M.J., Willett, B.J., Dunsford, T.H., Jarrett, O., and Neil, J.C.
Subjects:S Agriculture > SF Animal culture > SF600 Veterinary Medicine
Q Science > QR Microbiology > QR355 Virology
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation > Centre for Virus Research
Journal Name:Journal of Virology
Journal Abbr.:J. Virol.
ISSN:0022-538X
ISSN (Online):1098-5514

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