Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines

Hosie, M.J. , Osborne, R., Yamamoto, J.K., Neil, J.C. and Jarrett, O. (1995) Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines. Journal of Virology, 69(2), pp. 1253-1255.

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Publisher's URL: http://jvi.asm.org/cgi/content/abstract/69/2/1253

Abstract

Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is distinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutralizing antibody response and was retained when the challenge virus was propagated in an unrelated cell line.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Hosie, Professor Margaret and Neil, Professor James
Authors: Hosie, M.J., Osborne, R., Yamamoto, J.K., Neil, J.C., and Jarrett, O.
Subjects:S Agriculture > SF Animal culture > SF600 Veterinary Medicine
Q Science > QR Microbiology > QR355 Virology
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Journal of Virology
Journal Abbr.:J. Virol.
ISSN:0022-538X
ISSN (Online):1098-5514

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