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Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines

Hosie, M.J., Osborne, R., Yamamoto, J.K., Neil, J.C., and Jarrett, O. (1995) Protection against homologous but not heterologous challenge induced by inactivated feline immunodeficiency virus vaccines. Journal of Virology, 69 (2). pp. 1253-1255. ISSN 0022-538X

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Publisher's URL: http://jvi.asm.org/cgi/content/abstract/69/2/1253

Abstract

Whole inactivated virus vaccines from the FL4 cell line protected against challenge with homologous feline immunodeficiency virus (Petaluma strain) but not against a heterologous FIV isolate (GL-8) which is distinct from the Petaluma strain in virus neutralization. Protection was associated with a type-specific neutralizing antibody response and was retained when the challenge virus was propagated in an unrelated cell line.

Item Type:Article
Status:Published
Refereed:Yes
Glasgow Author(s):Hosie, Prof Margaret and Neil, Prof James
Authors: Hosie, M.J., Osborne, R., Yamamoto, J.K., Neil, J.C., and Jarrett, O.
Subjects:S Agriculture > SF Animal culture > SF600 Veterinary Medicine
Q Science > QR Microbiology > QR355 Virology
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation > Centre for Virus Research
Journal Name:Journal of Virology
Journal Abbr.:J. Virol.
ISSN:0022-538X
ISSN (Online):1098-5514

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