Effects of time of year and reproductive state on the proliferation and keratinisation of bovine hoof cells

MacCallum, A.J., Knight, C.H., Hendry, K.A.K., Wilde, C.J., Logue, D. and Offer, J.E. (2002) Effects of time of year and reproductive state on the proliferation and keratinisation of bovine hoof cells. Veterinary Record, 151(10), pp. 285-289. (doi: 10.1136/vr.151.10.285)

Full text not currently available from Enlighten.

Publisher's URL: http://dx.doi.org/10.1136/vr.151.10.285

Abstract

Cell proliferation and protein synthesis (keratinisation) were measured in vitro in hoof biopsy samples taken from two groups of seven heifers, the first calving in the winter and the second in the summer. Both parameters were significantly higher in summer than in winter irrespective of the heifers' reproductive state. The mean (se) measure of the rate of protein synthesis was 199 (27) dpm/microg DNA/hour in summer and 4 (1) dpm/microg DNA/hour in winter, and the equivalent values for cell proliferation (measured as DNA synthesis) were 375 (56) dpm/microg DNA/hour and 17 (4) dpm/microg DNA/hour. Changes around parturition depended on the time of the year. In the winter-calving heifers, the rates of proliferation and keratinisation increased significantly after calving from 22.3 (7.2) to 70.4 (16.6) and from 2.1 (0.7) to 12.4 (2.8) dpm/microg DNA/hour, respectively. In the summer-calving heifers, proliferation decreased from 388.2 (91.0) to 66.7 (9.6) dpm/microg DNA/hour but the rate of keratinisation did not change. Lesion scores and locomotion scores deteriorated after parturition, especially in the winter-calving group. The hooves were harder in summer than winter but their hardness was not affected by the heifers' reproductive state.

Item Type:Articles
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Maccallum, Dr Amanda and Logue, Professor David
Authors: MacCallum, A.J., Knight, C.H., Hendry, K.A.K., Wilde, C.J., Logue, D., and Offer, J.E.
College/School:College of Medical Veterinary and Life Sciences > School of Veterinary Medicine
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Veterinary Record
Journal Abbr.:Vet rec.
Publisher:B M J Group
ISSN:0042-4900
ISSN (Online):2042-7670

University Staff: Request a correction | Enlighten Editors: Update this record