Neuronal localization of simian varicella virus DNA in ganglia of naturally infected African green monkeys

Kennedy, P.G.E., Grinfield, E., Traina-Dorge, V., Gilden, D.H. and Mahalingam, R. (2004) Neuronal localization of simian varicella virus DNA in ganglia of naturally infected African green monkeys. Virus Genes, 28(3), pp. 273-276. (doi: 10.1023/B:VIRU.0000025774.19557.39)

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Abstract

<i>In situ</i> hybridization analysis of monkey ganglia 2 months after natural infection with simian varicella virus (SVV) revealed SVV DNA only in neurons. These findings parallel the detection of varicella zoster virus in neurons of latently infected human ganglia. Natural exposure to SVV provides a model system to study varicella latency.

Item Type:Articles
Keywords:Ganglia, neurons, varicella latency
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Kennedy, Professor Peter
Authors: Kennedy, P.G.E., Grinfield, E., Traina-Dorge, V., Gilden, D.H., and Mahalingam, R.
Subjects:Q Science > QH Natural history > QH426 Genetics
College/School:College of Medical Veterinary and Life Sciences
College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:Virus Genes
Publisher:Springer
ISSN:0920-8569
ISSN (Online):1572-994X

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