The end of the line for hookworm? An update on vaccine development

Devaney, E. (2005) The end of the line for hookworm? An update on vaccine development. PLoS Medicine, 2(10), e327. (doi:10.1371/journal.pmed.0020327)

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Publisher's URL: http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.0020327

Abstract

Human hookworms are parasitic nematodes infecting about 700 million individuals, largely in tropical regions of the world [1]. In endemic areas, most infected people carry a mixed worm burden, including Ascaris lumbricoides (roundworms), Trichuris trichuria (whipworms), and Ancylostoma duodenale and/or Necator americanus (both hookworms). Of these soil-transmitted helminths, hookworms are the most pathogenic because of their propensity to feed on blood, resulting in anaemia, particularly in those with low iron reserves such as children and women of reproductive age.

Item Type:Articles
Additional Information:This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Devaney, Professor Eileen
Authors: Devaney, E.
College/School:College of Medical Veterinary and Life Sciences > Institute of Infection Immunity and Inflammation
Journal Name:PLoS Medicine
Publisher:Public Library of Science
ISSN:1549-1277
ISSN (Online):1549-1676
Published Online:04 October 2005
Copyright Holders:© 2005 Eileen Devaney
First Published:First published in PLoS Medicine 2005 2(10): e327
Publisher Policy:Reproduced in accordance with the copyright policy of the publisher
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