Estimations of critical clear corneal incisions required for lens insertion in cataract surgery: a mathematical aspect

Qi, N., Lockington, D., Wang, L., Ramaesh, K. and Luo, X. (2022) Estimations of critical clear corneal incisions required for lens insertion in cataract surgery: a mathematical aspect. Frontiers in Physiology, 13, 834214. (doi: 10.3389/fphys.2022.834214)

[img] Text
268688.pdf - Published Version
Available under License Creative Commons Attribution.

1MB

Abstract

In a routine cataract operation cornea tissue may be damaged when an intra-ocular lens (IOL) injector of diameter between 1.467mm-2.011mm is inserted through an empirically designed 2.2mm corneal incision. We aimed to model and estimate the minimal length of the incision required to avoid wound tear. It was assumed that the damage was caused by tissue fracture at the tips of the incision, and this fracture could be studied using damage and fracture mechanics. The criterion of the damage was caused by a tear governed by the critical energy release rate (ERR) Gc, which is tissue dependent. Analytical and numerical studies were both conducted indicating the possibility of a safe and effective incision in cataract surgery. Six commonly used IOL injection systems were examined. Our results suggested that the recommended 2.2mm incision cannot be treated as a universal threshold. Quicker IOL insertion may reduce wound damage. It was also recommended to advance IOL injector via its minor axis, and to cut the tear preferably along the circumferential direction due to tissue orthotropy. This study provides useful information and a deeper insight into the potential for mechanical damage to the corneal wound in cataract surgery.

Item Type:Articles
Additional Information:We gratefully acknowledge the financial support from the National Natural Science Foundation of China (No. 11902181), the National Natural Science Foundation of Shandong Province (No. ZR2019QA014), and the United Kingdom EPSRC grants (EP/S030875/1 and EP/S020950/1).
Status:Published
Refereed:Yes
Glasgow Author(s) Enlighten ID:Luo, Professor Xiaoyu and Qi, Dr Nan and Ramaesh, Dr Kanna
Creator Roles:
Qi, N.Conceptualization, Methodology, Investigation, Visualization, Formal analysis, Writing – original draft
Ramaesh, K.Investigation, Writing – review and editing
Luo, X.Conceptualization, Methodology, Writing – review and editing
Authors: Qi, N., Lockington, D., Wang, L., Ramaesh, K., and Luo, X.
College/School:College of Medical Veterinary and Life Sciences
College of Science and Engineering > School of Mathematics and Statistics > Mathematics
Journal Name:Frontiers in Physiology
Publisher:Frontiers Media
ISSN:1664-042X
ISSN (Online):1664-042X
Copyright Holders:Copyright © 2022 The Authors
First Published:First published in Frontiers in Physiology 13:834214
Publisher Policy:Reproduced under a Creative Commons License

University Staff: Request a correction | Enlighten Editors: Update this record

Project CodeAward NoProject NamePrincipal InvestigatorFunder's NameFunder RefLead Dept
303232EPSRC Centre for Multiscale soft tissue mechanics with MIT and POLIMI (SofTMech-MP)Xiaoyu LuoEngineering and Physical Sciences Research Council (EPSRC)EP/S030875/1M&S - Mathematics
303231A whole-heart model of multiscale soft tissue mechanics and fluid structureinteraction for clinical applications (Whole-Heart-FSI)Xiaoyu LuoEngineering and Physical Sciences Research Council (EPSRC)EP/S020950/1M&S - Mathematics